Ingredients: Grape Seed (Semen Vitis vinifera)

Grapes with Seeds
Grapes (Vitis vinifera) have been heralded for their medicinal and nutritional value for thousands of years. Egyptians ate grapes at least 6,000 years ago, and several ancient Greek philosophers praised the healing power of grapes, usually in the form of wine. European folk healers made an ointment from the sap of grapevines to treat skin and eye diseases. Grape leaves were used to stop bleeding, inflammation, and pain, such as the kind brought on by haemorrhoids. Unripe grapes were used to treat sore throats, and dried grapes (raisins) were used for constipation and thirst. Round, ripe, sweet grapes were used to treat a range of health problems including cancer, cholera, smallpox, nausea, eye infections, and skin, kidney, and liver diseases.

But grapes, or the chemicals within them, a class of polyphenols known as ProanthoCyanidolic Oligomers (PCOs), have been touted as powerful antioxidants. Some people believe they could help treat a number of conditions, from heart disease to cancer to raging skin. There is also good clinical evidence that grape seed extract can help treat chronic venous insufficiency and edema.

A study of healthy volunteers found that taking grape seed extract substantially increased blood levels of antioxidants. Antioxidants are substances that destroy free radicals, which are harmful compounds in the body that damage DNA (genetic material) and even cause cell death. Scientists believe free radicals contribute to aging, as well as the development of a number of health problems, including heart disease and cancer.

The most pharmaceutically active components in V. vinifera extract are a class of polyphenols known as ProanthoCyanidolic Oligomers (PCOs). The natural purpose of these chemicals is to defend the tree against insects, bacteria and other microorganisms that attack the wine. The French chemist Jacques Masquelier first extracted Proanthocyanidolic Oligomers (PCOs), also known as oligomeric proanthocyanidins (OPCs), from grape seeds and pine bark in 1947. He later patented this process and continued his research on PCOs into the 1980s.

PCOs are often used in health supplements for their antioxidant activity. This property allows them to inhibit the reactions of free radicals that would otherwise damage the cells in your body, especially the membranes. Antioxidants therefore provide a large number of specific health benefits.

The most significant uses of pine bark extract relates to the value of PCOs as an antioxidant. The specific benefits include healthy inflammation management in addition to support for epidermal connective tissue (skin) and capillaries.

Major health benefits of PCOs for the Human Body

Besides many other health benefits, there three major benefits of a frequent Pine Bark Extract consumption for the human body are:

    1. Powerful antioxidant cell protection from harmful free radical molecules
    2. Strong vascular and capillary support – essential for nutrient delivery and cellular waste removal
    3. Potent skin collagen protection from collagen degradation
    4. Powerful Vitamin C Potentiator, intensifies Vitamin C uptake and effectiveness in the body, strengthening the body's immune system

Click here to read more about PCOs

The scientific research team behind CLINIVITA researches Vitis vinifera and PCOs for its health benefits in various therapeutic areas.